Getting Started
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How to Access clonoSEQ
Order clonoSEQ through Adaptive’s CLIA-certified, CAP-accredited, ISO 13485-certified laboratory in Seattle, Washington
Contact Adaptive to learn more about ordering clonoSEQ testing services for your patients.
We will walk you through the process of:
Creating an online portal account
Confirming important details about your institution/practice
Selecting preferences for how and to whom test results are delivered
Completing an online clonoSEQ Test Requisition Form (TRF)
The clonoSEQ testing service offers:
Actionable Results
Delivered within approximately 7 days (fresh specimens) or 14 days (stored specimens) from the date of sample receipt and reconciliation.*
Online Order Completion
Patient data is securely stored in our online portal, eliminating the need for repetitive manual data entry.
Automated Verification
Ensures each order includes all the required information, reducing the likelihood of follow-up calls or processing delays.
Shipping Materials Provided
Upon request, we can provide kits to help you collect and ship fresh, stored, and frozen specimens.
Secure Report Access
View and search results for your patients via our Diagnostics Portal, or opt-in to receive secure fax reports.
Stored Specimen Retrieval Support
Given permission, we can contact outside pathology labs to obtain access to stored diagnostic specimens for Clonality (ID) testing.
*Reconciliation ensures that all required information and documentation is correct for the patient, clinician, institution, order, and sample. In cases where a sample must be retrieved from a pathology lab and/or has been stored under certain conditions, reconciliation will add additional time to the testing process.
The content of this page is intended primarily for healthcare professionals.
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Find out how you can join the growing number of clinicians who are integrating clonoSEQ into their practice. Click here to request information on the clonoSEQ® Assay.
DATA WITH DEPTH. RESULTS WITH RELEVANCE.TM
The clonoSEQ testing process
When used to measure residual disease in lymphoid malignancies like B-cell acute lymphoblastic leukemia (ALL) and multiple myeloma, the clonoSEQ Assay requires two testing steps to be completed sequentially:
First: Clonality (Id) test
Then: tracking (MRD) test
Send specimens
with a completed clonoSEQ Test Requisition Form
Shipping address:
Adaptive Biotechnologies Corporation
Attention: Clinical Services
1551 Eastlake Avenue East, Suite 200
Seattle, WA 98102
Intake hours:
Monday–Saturday 8am to 5pm PST
Biological specimens can be received and reconciled on the days and times above. Samples cannot currently be received on Sundays.
Contact clinical services
HOURS OF OPERATION:
Monday–Friday
5:30am-5:00pm PST
Documents to assist with ordering clonoSEQ
clonoSEQ Test
Specimen Requirements
ABN Information Sheet
clonoSEQ Diagnostic Portal Overview(for online order completion and results delivery)
ABN Form
clonoSEQ Reports Overview
Billing Process and
Coverage Policy Overview
Ordering clonoSEQ: Helpful Hints
Visit Adaptive-Assist.com to learn more about our Adaptive Assist Patient Support Program
Frequently asked questions
This is my first time ordering the clonoSEQ Assay. How do I get started?
All clinicians who wish to order must first complete a Physician Registration Form. This form can be obtained from and returned to Adaptive Clinical Services. Because this form will be updated on occasion, clinicians who have ordered in the past may be contacted by Adaptive to reconfirm their registration details.
In addition to the Registration Form, Adaptive will need to work with hospital-based institutions or practices treating hospital-registered patients to put in place a Laboratory Services Agreement which establishes the features of our service offering and agreed-upon billing terms. We will work with you and/or a colleague you designate to establish a mutually-beneficial agreement. Please contact Clinical Services or your Diagnostic Key Account Manager with questions about this process.
How do I place a clonoSEQ order?
All Test Requisition Forms (TRFs) must be completed through our easy-to-use, secure online Diagnostic Portal. Please contact Clinical Services for information on how to set up an account.
What are the requirements for shipping?
Once you have completed a TRF within the Diagnostic Portal, please print, sign and date the TRF.
- If you are shipping a specimen for testing, you must include the signed TRF inside the box containing the specimen.
- If you are requesting pathology retrieval assistance from Adaptive, please send the TRF by secure email or fax to Adaptive Clinical Services.
If you indicate on the TRF that your test order should be billed to the patient’s insurance, a front/back copy of the patient’s insurance card must be included with the TRF.
If you are shipping a specimen, please be sure to:
- Follow the preparation and shipping instructions specified in the clonoSEQ Test Specimen Requirements, which are accessible in the documents section above.
- Label the specimen tube with two unique patient identifiers to ensure proper identification.
Adaptive can provide a clonoSEQ Fresh Collection Kit and a clonoSEQ Frozen Shipper. To order, please contact Clinical Services. You may also use your own packaging materials; ship to the address listed at the top of this guide.
How do I request pathology retrieval assistance?
If desired, Adaptive can assist with the retrieval of archived pathology specimens. Requests for this assistance must be indicated in the Specimen Information section of the TRF. To enable pathology specimen retrieval, the patient’s complete pathology report must be included with the signed TRF.
How long will it take to get patient results back?
Adaptive aims to provide accurate and timely patient results. You can expect to receive results in approximately 7 days for fresh specimens and 14 days for stored specimens, measured from the date that an appropriate sample is received and reconciled in Adaptive’s Seattle laboratory. Samples that arrive without requisite information will require additional time to reconcile.
Adaptive must have a valid Clonality (ID) Test result in order to generate a Tracking (MRD) Test result for a given patient. Delivery of clinical reports containing MRD results will be delayed until a corresponding Clonality (ID) result becomes available.
If you are requesting Adaptive assistance with pathology specimen retrieval, please note that lab response times to our requests vary considerably. The turnaround times listed above are measured from the date Adaptive receives and reconciles an appropriate specimen. Turnaround times do not include time required for specimen retrieval. If specimen retrieval is urgent, Adaptive recommends that the clinician request and submit the specimen directly from the pathology lab.
How will I receive the patient report?
You can easily access patient results through Adaptive’s Diagnostic Portal—the same portal that you will use to complete clonoSEQ TRFs.
- The Diagnostic Portal enables you to filter and sort patient reports so that you can find specific reports quickly and easily.
- Upon release of new patient results, you will receive an email notification with a direct link to your patient’s report. You can also choose to have patient results delivered via secure fax.
- You will only receive one email or fax notification per order, at the time when all results for the patient's order are available. Results of individual tests within an order will always be available in real-time in the Diagnostic Portal.
Request information
Citations
- Wu D, et al. Sci Transl Med. 2012;4(134):134ra63.
- Carlson C, et al. Nat Commun. 2013;4:2680.
- Pulsipher M, et al. Blood. 2015;125(22):3501-8.