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ABOUT clonoSEQ®

Why clonoSEQ?

clonoSEQ can detect 1 single cancer cell among a million healthy cells1*

What does 1 in a million mean to you? It means that you and your doctor can pinpoint where you are on your blood cancer journey. By precisely tracking MRD both during and after treatment, you and your doctor can be more informed about your response to therapy—and can plan next steps accordingly.1

*If enough sample material is provided.

With clonoSEQ, you and your doctors can help:

MONITOR

your cancer by assessing treatment response and changes in disease burden1

MANAGE

decisions with an ongoing understanding of your long-term outcomes1

MOVE FORWARD

with more confidence when planning for all of life’s moments

References to “cancer” on this webpage refer specifically to multiple myeloma, CLL, and B-ALL. References to “sample” refer to bone marrow or blood from patients with CLL and bone marrow from patients with multiple myeloma or B-ALL. Talk to your doctor about your options if you have another type of blood cancer and are interested in MRD testing.

Understanding the clonoSEQ patient journey

clonoSEQ is sensitive enough to find a single cancer cell among a million healthy cells if enough sample material is provided.1

How does clonoSEQ work?

clonoSEQ identifies the specific DNA sequence(s) associated with your cancer and tracks them over time.1

Testing regularly can help monitor changes in your disease.

How can clonoSEQ results help shape your care plan?

The results from MRD testing with clonoSEQ, along with other clinical information, may help your doctor tailor your care to changes in your disease level.2-4

Talk with your doctor to find out if a goal of MRD negativity is right for you.

Why is ongoing clonoSEQ testing useful?

clonoSEQ gives you and your doctor a personalized way to track—and talk about—your body’s individual response to treatment.

Regular MRD testing can give you and your doctor additional important information to make informed decisions at each stage of treatment.2-4

Why should I test when I'm not experiencing any symptoms?

Even if you aren’t experiencing any symptoms, you may still feel anxious or worried that the cancer will return.

Routine MRD testing may help detect the return of cancer before physical signs and symptoms arise, so you and your doctor can respond—and plan for the future.2-4

Explore stories from patients like you

See how knowing your MRD status can help you manage treatment decisions

MYELOMA CLL B-ALL

Talk to your doctor about clonoSEQ

Here are some questions to help you start a conversation with your doctor about how MRD testing with clonoSEQ can help inform your treatment plan.

  • What is MRD?
  • Is MRD testing with clonoSEQ right for me?
  • I heard that clonoSEQ can identify 1 cancer cell out of 1 million cells with sufficient sample. Why does that matter to someone like me?1
  • What can MRD testing with clonoSEQ tell me about my cancer?
  • How will MRD results from a clonoSEQ test affect my treatment plan?
  • How often should I get a clonoSEQ test?
  • What does a positive or negative MRD status with clonoSEQ mean for me?
  • Is the goal of MRD negativity with clonoSEQ right for me?

Save or send these questions

If you have multiple myeloma, CLL, or B-ALL, talk with your doctor about tracking your MRD status with clonoSEQ.

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This page is intended for a US-based audience.

clonoSEQ® is an FDA-cleared test used to detect minimal residual disease (MRD) in bone marrow from patients with multiple myeloma or B-cell acute lymphoblastic leukemia (B-ALL) and blood or bone marrow from patients with chronic lymphocytic leukemia (CLL). CLL Clonality (ID) Tests will also produce an IGHV status result, which is provided as a CLIA-validated laboratory developed test (LDT) but which has not been cleared or approved by the FDA. Additionally, clonoSEQ is available for use in other lymphoid cancers and specimen types as a CLIA-validated LDT. For important information about the FDA-cleared uses of clonoSEQ including test limitations, please visit clonoSEQ.com/technical-summary.

clonoSEQ is only available by prescription from a licensed healthcare professional. Results may vary. Talk to your healthcare provider to see if clonoSEQ testing is right for you. For important information about the FDA-cleared uses of clonoSEQ including test limitations, please visit clonoSEQ.com/technical-summary.

References

  • Al-Sawaf O, et al. J Clin Oncol. 2021;JCO2101181.
  • Friend B, et al. Pediatr Blood Cancer. 2020;67(2):e28079.