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Now available
for DLBCL

The first Medicare-reimbursed MRD
assay for patients with DLBCL,
available as a CLIA-validated LDT.

$0 cost for Medicare patients—and with
no frequency restrictions.

LEARN MORE

Ordering the Test

Bring advanced MRD detection to your practice

How to make your first order:

  1. 1Contact us using the form below to create an online portal account. If you already have an account, log in here
  2. 2Confirm important details about your institution/practice and ordering preferences
  1. 3Complete an online clonoSEQ Test Requisition Form (TRF)
  2. 4Ship your samples and wait for results on the online portal

Register to order clonoSEQ

    Please confirm that you agree you are requesting medical information and certify that you are a physician or healthcare provider, that you are not including any Protected Health Information (PHI), and that the terms of the Adaptive Online Privacy Policy, Terms of Use, HIPAA Notice, and any other Adaptive policies apply.

    If you need to speak with Adaptive’s Clinical Services team, please:

    Call 1 (888) 552-8988 from 5:30 AM – 5 PM PT, opt. 1, Monday through Friday,
    or email clinicalservices@adaptivebiotech.com

    Laboratory Shipping Address

    Adaptive Biotechnologies Corporation
    Attention: CLIA Lab
    1551 Eastlake Avenue East, Suite 200
    Seattle, WA 98102

    Intake Hours:

    Monday–Saturday
    8 AM to 5 PM PT

    Biological specimens can be received and accessioned on the days and times above. Samples cannot currently be received on Sundays.

    Licenses

    View our CAP Accreditation or our CLIA license.

    Biological specimens can be received and accessioned on the days and times above. Samples cannot currently be received on Sundays.

    The clonoSEQ testing service offers:

    Actionable results

    Delivered within approximately 7 days (fresh specimens) or 14 days (stored specimens) from the date of sample receipt and reconciliation.*

    Online ordering completion

    Patient data is securely stored in our online portal, eliminating the need for repetitive manual data entry.

    Automated verification

    Ensures each order includes all the required information, reducing the likelihood of follow-up calls or processing delays.

    Shipping materials provided

    Upon request, we can provide kits to help you collect and ship fresh, stored, and frozen specimens.

    Secure report access

    View and search results for your patients via our Diagnostics Portal, or opt-in to receive secure fax reports.

    Stored specimen retrieval support

    Given permission, we can contact outside pathology labs to obtain access to stored diagnostic specimens for Clonality (ID) testing.

    *Reconciliation ensures that all required information and documentation is correct for the patient, clinician, institution, order, and sample. In cases where a sample must be retrieved from a pathology lab and/or has been stored under certain conditions, reconciliation will add additional time to the testing process.

    Ordering walkthrough

    Questions about ordering clonoSEQ?
    Call 1 (888) 552-8988

    Frequently asked questions

    This is my first time ordering clonoSEQ. How do I get started?

    All clinicians who wish to order must first complete a Physician Registration Form. This form can be obtained from and returned to Adaptive Clinical Services. Because this form will be updated on occasion, clinicians who have ordered in the past may be contacted by Adaptive to re-confirm their registration details.

    In addition to the Registration Form, Adaptive will need to work with hospital-based institutions or practices treating hospital-registered patients to put in place a Laboratory Services Agreement which establishes the features of our service offering and agreed-upon billing terms. We will work with you and/or a colleague you designate to establish a mutually beneficial agreement. Please contact Clinical Services or your Diagnostic Key Account Manager with questions about this process.

    How do I place a clonoSEQ order?

    All Test Requisition Forms (TRFs) must be completed through our easy-to-use, secure online Diagnostic Portal. Please contact Clinical Services for information on how to set up an account.

    What are the requirements for shipping?

    Once you have completed a TRF within the Diagnostic Portal, please print, sign and date the TRF.

    • If you are shipping a specimen for testing, you must include the signed TRF inside the box containing the specimen.
    • If you are requesting pathology retrieval assistance from Adaptive, please send the TRF by secure email or fax to Clinical Services.

    If you indicate on the TRF that your test order should be billed to the patient’s insurance, a front/back copy of the patient’s insurance card must be included with the TRF.

    If you are shipping a specimen, please be sure to:

    • Follow the preparation and shipping instructions specified in the clonoSEQ Test Specimen Requirements, which are accessible on the Downloadable Resources page.
    • Label the specimen tube with 2 unique patient identifiers to ensure proper identification.

    Adaptive can provide a clonoSEQ Fresh Collection Kit and a clonoSEQ Frozen Shipper. To order, please contact Clinical Services. You may also use your own packaging materials; ship to the address listed at the top of this page.

    How do I request pathology retrieval assistance?

    If desired, Adaptive can assist with the retrieval of archived pathology specimens. Requests for this assistance must be indicated in the Specimen Information section of the TRF. To enable pathology specimen retrieval, the patient’s complete pathology report must be included with the signed TRF.

    How long will it take to get patient results back?

    Adaptive aims to provide accurate and timely patient results. You can expect to receive results in approximately 7 days for fresh specimens and 14 days for stored specimens, measured from the date that an appropriate sample is received and reconciled in Adaptive’s Seattle laboratory. Samples that arrive without requisite information will require additional time to reconcile.

    Adaptive must have a valid Clonality (ID) Test result in order to generate a Tracking (MRD) Test result for a given patient. Delivery of clinical reports containing MRD results will be delayed until a corresponding Clonality (ID) result becomes available.

    If you are requesting Adaptive assistance with pathology specimen retrieval, please note that lab response times to our requests vary considerably. The turnaround times listed above are measured from the date Adaptive receives and reconciles an appropriate specimen. Turnaround times do not include time required for specimen retrieval. If specimen retrieval is urgent, Adaptive recommends that the clinician request and submit the specimen directly from the pathology lab.

    How will I receive the patient report?

    You can easily access patient results through Adaptive’s Diagnostic Portal—the same portal that you will use to complete clonoSEQ TRFs.

    • The Diagnostic Portal enables you to filter and sort patient reports so that you can find specific reports quickly and easily.
    • Upon release of new patient results, you will receive an email notification with a direct link to your patient’s report. You can also choose to have patient results delivered via secure fax.
    • You will only receive one email or fax notification per order, at the time when all results for the patient’s order are available. Results of individual tests within an order will always be available in real-time in the Diagnostic Portal.

    This page is intended for a US-based audience.

    clonoSEQ® is available as an FDA-cleared in vitro diagnostic (IVD) test service provided by Adaptive Biotechnologies to detect minimal residual disease (MRD) in bone marrow from patients with multiple myeloma or B-cell acute lymphoblastic leukemia (B-ALL) and blood or bone marrow from patients with chronic lymphocytic leukemia (CLL). CLL Clonality (ID) Tests will also produce an IGHV status result, which is provided as a CLIA-validated laboratory developed test (LDT) but which has not been cleared or approved by the FDA. Additionally, clonoSEQ is available for use in other lymphoid cancers and specimen types as a CLIA-validated LDT. For important information about the FDA-cleared uses of clonoSEQ including test limitations, please visit clonoSEQ.com/technical-summary.